eSCAPing high cholesterol
نویسندگان
چکیده
منابع مشابه
Escaping High Viral Load Exhaustion
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in the face of a high quantity of viral antigen. Although they do not appear to exert immunological pressure in vivo, these CD8 cells are not cla...
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سابقه و هدف: هیپرکلسترولمی یکی از فاکتورهای خطر بیماری‌های قلبی ـ عروقی است و افزایش کلسترول خون سلامت عمومی را تحت تاثیر قرار داده و میزان مرگ و میر ناشی از بیماری‌های قلبی ـ عروقی را افزایش می‌دهد. تغذیه با رژیم پرکلسترول باعث افزایش میزان LDL و همچنین کاهش فعالیت گیرنده‌های LDL در کبد می‌شود. اکسیداسیون لیپوپروتئین موجود در دیواره عروق، باعث پیشرفت بیماری آتروسکلروز می‌شود. شواهد چندی حاکی ...
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Background: Diabetes is a prevalent chronic disease around the world. To evaluate risk of diabetes comprehensively, we developed a score model for the risk prediction with HDL-C as a protective factor. Methods: We extracted physical examination data of 2728 individuals. The data contain 18 demographic and clinical variables. To identify the statistical significant feature variables, the backwa...
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Two very different articles in this issue deal with the same important subject: workflow redesign. It’s a topic that is at the same time important and often slighted, largely because workflow – the way we do what we do day after day – tends to become such a well-traveled route that we may forget that other ways may lead us to the same end more quickly and efficiently. When workflow issues do ...
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One study with two distinct sections was conducted to identify factors facilitating escape from homelessness. In section one, 58 homeless individuals rated possible facilitators of escape (factors they believed would help them become more independent and self-sufficient). In section two, 80 participants who had already exited homelessness rated the same facilitators (factors that would have hel...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2002
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd716